Injectable Procedures
Neurotoxin: Botox, Letybo and Dysport
Neurotoxins are prescription medicines that temporarily relax certain facial muscles. At Smiley Aesthetics, our licensed medical providers offer three FDA-approved options: Botox Cosmetic, Letybo and Dysport. Your provider will help you decide which one fits you.
What It Treats
All three are FDA-approved to temporarily improve the look of moderate to severe frown lines between the eyebrows in adults (Dysport: adults younger than 65). Botox Cosmetic is also FDA-approved for crow’s feet, forehead lines and platysma bands (vertical bands in the neck).
At a Glance
What each manufacturer says about its own product.
| Botox Cosmetic | Letybo | Dysport | |
|---|---|---|---|
| Made by | AbbVie (Allergan Aesthetics) | Hugel | Galderma |
| Active ingredient | onabotulinumtoxinA | letibotulinumtoxinA-wlbg | abobotulinumtoxinA |
| FDA-approved cosmetic use | In adults: frown lines between the eyebrows, crow’s feet, forehead lines and neck bands (platysma bands) | In adults: frown lines between the eyebrows | In adults younger than 65: frown lines between the eyebrows |
| Results begin (manufacturer says) | May start in 24–48 hours; full results in 30 days | Visible results in as little as 1–3 days | As little as 24 hours; typically within 2–3 days |
| Results may last (manufacturer says) | Up to 4 months | Up to 4 months | Up to 5 months |
| Repeat treatment (from the label) | Not studied more often than every 3 months | Not more often than once every 3 months | Not sooner than 12 weeks after the last treatment |
| Units | Not interchangeable with other botulinum toxin products | Not interchangeable with other botulinum toxin products | Not interchangeable with other botulinum toxin products |
This table shows what each company says about its own product. These products were not compared head to head, so please do not read it as one being better than another. Individual results vary.
Meet the Three Options
Plain-language facts from each manufacturer.
Botox Cosmetic
onabotulinumtoxinA • AbbVie
A prescription medicine injected into muscles. FDA-approved, in adults, to temporarily improve the look of moderate to severe frown lines between the eyebrows, crow’s feet, forehead lines, and vertical bands connecting the neck and jaw (platysma bands).
The manufacturer says you may start to see results in 24–48 hours, with full results in 30 days, lasting up to 4 months. The FDA label gives about 3–4 months for frown lines.
Letybo
letibotulinumtoxinA-wlbg • Hugel
A prescription medicine injected into muscles. Approved by the FDA in 2024 to temporarily improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults.
The manufacturer says visible results can come in as little as 1–3 days and may last up to 4 months. In its studies, the most common side effect was headache.
Dysport
abobotulinumtoxinA • Galderma
A prescription medicine injected into muscles. For cosmetic use, FDA-approved to temporarily improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in adults younger than 65.
The manufacturer says results can appear in as little as 24 hours, typically within 2–3 days, and may last up to 5 months. Those figures come from the company’s own studies and are not a promise for every patient.
Neurotoxin Pricing
$9–$11 per unit
Neurotoxin at Smiley Aesthetics is priced per unit. Our price is $9–$11 per unit at all of our locations, for Botox Cosmetic, Letybo and Dysport. Your total depends on your treatment plan and what specials, coupons, or promotions we have going on at any given clinic! Please contact us or visit any location for a personalized consultation and exact pricing.
Units are different for each product and cannot be compared or converted, so the number of units you need can differ from one product to another. Price per unit alone is not a full comparison.
What to Expect at Your Visit
Consultation
Every visit starts with a conversation about your goals and your health. Please tell your provider about your medical history and every medicine you take, including antibiotics, muscle relaxants, allergy, cold and sleep medicines, and any botulinum toxin you have had in the last four months.
Treatment
Your provider will decide the plan with you and give the injections. Individual results vary. Your provider will talk with you about how often to come back.
Frequently Asked Questions
Which neurotoxin is right for me?
That is a decision for you and your licensed provider. It depends on the area you want to treat, your health, your medicines and your goals. We are happy to walk you through the options at a consultation.
Are the units the same across brands?
No. The units of each product are different and cannot be compared or converted. Each manufacturer says this in its safety information.
Do I need a consultation first?
Yes. A licensed medical provider will review your goals, medical history and medicines before recommending a treatment plan.
Can I get treated if I am pregnant or breastfeeding?
Tell your provider if you are pregnant, plan to become pregnant or are breastfeeding. For each product, it is not known whether it can harm an unborn baby or pass into breast milk. Your provider will review this with you.
Does Dysport contain milk protein?
Dysport should not be used by people who are allergic to cow’s milk protein. Tell your provider about any allergies before treatment.
Related reading: How Much Does Botox Cost in Nashville? (2026 Pricing Guide) · Masseter Botox in Nashville: Jaw Slimming and FDA Status
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Important Safety Information
These are prescription medicines. This is a summary, not a complete list of risks. Please read each full Prescribing Information and Medication Guide and talk with your provider.
All three: boxed warning, distant spread of toxin effect
The effects of botulinum toxin products may spread from the area of injection to other parts of the body. Symptoms can start hours to weeks after injection. They can include swallowing and breathing problems, which can be life threatening, and there have been reports of death. Other symptoms include muscle weakness all over the body, double or blurred vision, drooping eyelids, hoarseness or voice change, trouble saying words clearly, and loss of bladder control. Get medical help right away if you have any of these. These problems can make it unsafe to drive or do other dangerous activities.
Botox Cosmetic
- Do not receive it if you are allergic to Botox Cosmetic or any of its ingredients, are allergic to another botulinum toxin product, or have a skin infection at the planned injection site.
- Tell your provider if you have a muscle or nerve disease such as ALS, myasthenia gravis or Lambert-Eaton syndrome, if you plan to have surgery, have had face surgery, have trouble raising your eyebrows, or have drooping eyelids.
- The most common side effects in studies were eyelid droop (frown lines), eyelid swelling (crow’s feet), and headache and brow droop (forehead lines). Dry eye can also happen.
- Serious allergic reactions have been reported.
- To report side effects, call AbbVie at 1-800-678-1605, or FDA at 1-800-FDA-1088 or fda.gov/medwatch.
Botox Cosmetic full Prescribing Information | Medication Guide
Letybo
- Do not receive it if you are allergic to any botulinum toxin product or any ingredient in Letybo, or have an infection at the planned injection site.
- Tell your provider about heart problems, breathing or swallowing problems, nerve or muscle diseases, dry eye, planned surgery, drooping eyelids, and every medicine you take, including antibiotics.
- The most common side effect in studies was headache (2%).
- Serious allergic reactions have been reported. Use caution if you have heart disease.
- To report side effects, call Hugel at 1-888-674-5355, or FDA at 1-800-FDA-1088 or fda.gov/medwatch.
Letybo full Prescribing Information
Dysport
- Do not receive it if you are allergic to Dysport or any ingredient, are allergic to cow’s milk protein, have had an allergic reaction to another botulinum toxin (such as Myobloc, Botox or Xeomin), or have a skin infection at the planned injection site.
- Tell your provider about muscle or nerve diseases (such as ALS, myasthenia gravis or Lambert-Eaton syndrome), breathing or swallowing problems, bleeding problems, diabetes, heart rhythm problems, surgery, drooping eyelids, and every medicine you take.
- Common side effects include nose and throat irritation, headache, injection site pain or skin reaction, upper respiratory infection, eyelid swelling, eyelid drooping, sinus inflammation and nausea. Dry eye has also been reported. Serious allergic reactions have occurred.
- It is not known whether Dysport is safe or effective for people younger than 18 for glabellar lines, or for other wrinkles.
- To report side effects, call FDA at 1-800-FDA-1088 or fda.gov/medwatch.
