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Welcome to Smiley Aesthetics

Knoxville

525 Union Avenue, Knoxville, TN 37902

Same Day Appointments

With flexible hours and mobility, we are able to offer same day appointments in most of the locations we serve.

Extensive Network

Our team of experienced injectors span multiple states, we can provide coverage for the entire states, including rural areas.

Expert Staff

Our injectors are highly trained and receive ongoing education to ensure their skills and knowledge remain current and up-to-date.

Knoxville, TN

Welcome To Smiley Aesthetics Med Spa In Knoxville, Tennessee

Welcome to Smiley Aesthetics, the best Medspa in Knoxville, Tennessee! Our clients love us for our exceptional service, expertise, and personalized care. Owning your beauty starts from the inside out, so we offer a range of high-end health and wellness products to help you look and feel your best.

Located on Union Avenue, our expert team of medical professionals is dedicated to helping you achieve your beauty goals and enhance your natural beauty. We provide the highest quality aesthetic services in a comfortable and welcoming environment.

Smiley Services

Our range of high-end products, services, and personalized treatments will help you achieve your goals and enhance your natural beauty. Looking for the best medspa? You’ve found it.

Injectables

We offers a variety of injectable treatments to help reduce fine lines and wrinkles, augment lips, jaws, or cheeks, and melt away fat. We use industry-leading Allergan injectables to provide high-quality treatments that enhance your natural beauty.

Collagen Elixer

Collagen is essential for healthy skin, hair, nails, and joints. Our marine-based collagen elixir nourishes your body’s natural collagen while supplementing the 1% loss each year after 30 years of age. Our Medspa in Nashville offers a variety of health and wellness products to help you look and feel your best.

Weight Management Treatments

Looking and feeling your best starts from the inside out. That’s why we offer Isagenix’s weight management systems, which have been clinically proven to help you lose weight, increase your energy levels, and support your overall health. Our Nashville team will create a personalized plan to fit your needs and help you achieve your goals.

Vegan Skin Care Line

We offers a range of high-quality, vegan skin care products to refresh and revitalize your skin. The right skincare routine can help you look and feel your best, so we provide various vegan options to fit your needs.

The Smiley Difference

We offer only the best products and services

Whether you’re interested in our Semaglutide Weight Loss program, Cool Sculpting, Botox, Dermal Fillers, or Semaglutide Injections, we have the expertise and state-of-the-art technology to help you look and feel your very best. Our personalized approach to aesthetics means that we take the time to listen to your concerns and create customized treatment plans that are tailored to your unique needs.

Ready to see the Smiley difference? Follow us on Instagram for a behind-the-scenes look at our spa and treatments, and check out our glowing reviews on Google. If you’ve loved your experience with us, we’d be thrilled if you shared your feedback with a review—it means the world to us!

Meet Our Team

Alex Hoskins, RN | Clinic Manager

Alex Hoskins, RN | Clinic Manager

Alex is a registered nurse with 5 years of clinical experience in the ICU and ER, along with 2 years as a skilled aesthetic injector. She is passionate about delivering subtle, natural-looking enhancements that elevate her patients’ natural beauty. With a strong focus on safety, education, and personalized care, Alex strives to create a welcoming environment where clients feel heard, confident, and empowered at every visit.

Jazmine McClendon, RN | Clinic Injector

Jazmine McClendon, RN | Clinic Injector

Jazmine is a Registered Nurse with over 6 years of clinical experience, including a background in the ICU, and over 2 years as a nurse injector in the aesthetic space. She specializes in natural-looking enhancements that elevate, not change, your features.

With a strong focus on safety, education, and personalized treatment plans, Jazmine believes the best results come from trust, transparency, and attention to detail. She is known for her gentle technique and ability to create a comfortable, supportive experience where clients feel confident, informed, and truly cared for.

Our Price List

View Price List

Services & treatments to reach your beauty goals

At Smiley Aesthetics, we’re committed to providing exceptional service, expertise, and personalized care. Our range of high-end products, services, and personalized treatments will help you achieve your goals and enhance your natural beauty. If you’re looking for the best medspa, look no further than Smiley Aesthetics.

Smiley Aesthetics Memberships

6 Month Minimum Commitment Required on All Memberships

Platinum Membership

$349/Month | $3839/Annual

The Smiley Platinum Membership is designed for a comprehensive approach to your treatment plan! Covering multiple services so you can truly use the membership and tailor it to your treatment plan and needs.

Your membership includes the following:

  • One free B12 or Lipo Shot
  • One Red Light Therapy Session
  • $9/Unit Botox
  • 20% off Skincare

– AND –

Your choice of one of the following treatments once a month:

  • Single area of Scarlet RF or Microneedling
  • 45-minute Aquafirme Hydrating Facial 
  • 45-minute Aquafirme Derive Hair Restoration
  • IPL Photofacial
  • Single Area of Laser Hair Removal
  • One BioRePeel
  • Free Exosome Add-on with Any Treatment

Smiley Piggy Bank

$100/Month | $200/Month

Looking for a smart way to save for your future aesthetic treatments while enjoying exclusive discounts? The Smiley Piggy Bank Membership allows you to set aside funds each month for any treatment of your choice while unlocking special member-only savings.

With this membership, you’ll receive:

  • 10% off all treatments and products (excluding Botox and monthly specials)
  • Exclusive Botox pricing at just $10 per unit
  • The flexibility to use your savings on any service whenever you’re ready for your next treatment

Start saving today and invest in your beauty on your own terms!

What people say about Smiley Aesthetics

Take the first step toward a more beautiful you

At Smiley Aesthetics, we’re dedicated to guiding you on your journey to feeling and looking your best. Reach out today to book a consultation and discover our current CoolSculpting promotion for a more beautiful you.